NAGARJUNA INTRODUCES IN INDIA THE WORLD'S BEST & UNIQUE MITICIDE
MANUFACTURED BY SANKYO AGRO CO., LTD, JAPAN

Introduction Salient features Mode of action Product features Milbeknock - efficacy

 

INTRODUCTION:

Milbeknock is the world's best acaricide having Milbemectin as the active ingredient. Milbeknock was developed from fermented metabolites of actinomyces, Streptomyces hygroscopicus sub sp. aureolacrimosus and was invented by M/s Sankyo Agro Co. Ltd, Japan. It belongs to Milbemycins group and has excellent miticidal properties. Milbeknock is a popular acaricide in all developed countries including Japan.

Milbeknock has two analogues in the structure namely MA3 and MA4.
Milbemycin A3:R = CH3
Milbemycin A4:R = CH2CH3

Top

SALIENT FEATURES OF INDEX:

  1. It is a natural substance produced by the fermentation of a species of actinomyces. Streptomyces hygroscopicus sub sp. aureolacrimosus.

Streptomyces hygroscopicus
sub sp. aureolacrimosus
  1. Milbeknock has a strong miticidal action and is effective on all stages of mites viz., egg, nymph and adult.

EGGS

EGGS

EGGS
  1. Milbeknock has a long lasting control of mire population. The reasons hereunder are,
    • Milbeknock is effective at all growth stages of mites.
    • Milbeknock has suppressive effect on reproduction (oviposition). Mites fail to lay normal eggs if Milbeknock remain at levels lower than the lethal dosage. Sublenthal level will also effect reproduction.
    • Milbeknock has no significant impact on beneficials.
  2. Milbeknock has a good translaminar activity in the plant system. Spray fluid deposited on upper surface translocates to the lower surface & kills the target mites.

  1. Milbeknock has a unique mode of action on the mites nervous sytem. Milbeknock acts a agoinst of GABA (g-Amino butyric acid) in insect peripheral nervous system.
  2. Milbeknock has a short pre-harvest interval and is highly safer than any other conventional acaricides.
  3. Milbeknock has a very safe toxic profile to mammals.
  4. Milbeknock does not have any significant impact on honeybees.
  5. Milbeknock has been recognized as a "REDUCED RISK PESTICIDE" by "US-EPA" (May 2000) and was approved as "GNO" (The Dutch CTB) (GNO means crop production product of natural origin).


Top

MODE OF ACTION OF INDEX

Milbeknock has a unique mode of action, which is different from other conventional miticides. That is, Milbeknock acts on the nervous system mediated with inhibitory neurotransmitter, GABA (g-Amino butyric acid). As a result mites and insects treated with Milbeknock die without showing any movement nor excitary actions.

Milbeknock is a fermentation metabolite and when sprayed on the crop, it acts immediately on mites. Mites become inactive and remain inactive for 2-3 days during which they neither feed nor move. This state is called moribund stage. Then the mites die a depresant death with no change in colour and appearance. Thus, Milbeknock is very effective and ensures longer period of protection. Since, Milbeknock gives long lasting control of the pest, the number of sprays can be reduced.

Schematic representation of the inhibition of GABA in the mites nervous system by Milbeknock:

Nerve transmission in mite:

Nerve transmission in mite treated with Milbeknock:


Top

Milbeknock - Product features

FEATURE

ADVANTAGE

Natural Compound

Eco-friendly, fits well in IPM and organic farming.

Unique mode of action

Kills all stages of mites and those reported resistant to OP's, other miticides including abamectin.

Longer persistence

Effective against successive generations - consequently the frequency of application is reduced.

Suppressive oviposition

Stops the growth of population. Mites do not lay fertile eggs.

High translaminar action

Mite present in untreated leaf surface area is also killed.

Resistance to miticide not reported

Entire mite population is sussceptible. High morality.

Safe to natural enemies

Specifically targeted against phytophagous mites. Quite safe to predatory mites.

Cleared by US EPA as "Reduced Risk Pesticides" (May 2000) & approved as 'GNO by Dutch CTB'.

Very safe. Can be applied at any time.

No resurgence

Does not cause ecological upset which may result in resurgence of secondary pest.

Highly compatible

Compatible with commonly used pesticides

Not phytotioxic

No dent/scorching on leaves, flowers vegetables and fruits.

Low dosage as compared to any other miticides.

Reduction in the amount of insecticides in the environment.

Cost effective

Yield increase, good market acceptability and has export value and good profit.

Fast degarding activity

Milbeknock degrades quickly in the environment leaving no residues on the crop.

Milbeknock use Recommendations on Rose:

Target Mite

Two spotted spider mite

Scientific Name

Tetranychus urticae koch

Dose

180ml/acre (400lit of spray fluid)

Rate of dilution

0.45 ml/lit of water

When should Milbeknock spray be taken up?

Control measures should be initiated after the sppearance of mites (preferably mites not exceeding 5 per leaf to ensure better protection).


Top

Milbeknock - efficacy on other mite species

Nagarjuna has conducted in-house and university trials extensively on the efficacy of Milbeknock on different mite species and confirmed the efficacy with the following Dosages/Dilutions.
Aculops pelekassi
Panonychus ulmi

 

Common Name

Scientific Name

Milbeknock (Rate of dilution)

White mite

Polyphagatarsonemus latus

0.65ml/L

Red spider mite

Tetranychus urticae

Aceria lycopersici

Tetranychus macfarlanei

Tetranychus yusti

Oligonychus coffeae

Tetranychus neocalinodicus

0.65 ml/L

European redmite

Panonychus ulmi

1.0 ml/L

Purple mite

Calacarus carinatus (Green)

1.0 ml/L

Pink mite

Acaphilla theae

1.0 ml/L

Pale mite

Acaphyllisa parindiae kelfer

1.0 ml/L

Scarlet mite

Brevipalpus australis

1.0 ml/L

Pink citrus mite

Aculops pelekassi

1.0 ml/L

Citrus red mite

Panonychus citri

1.0 ml/L


Tetranychus urticae
Polyphagotarsonemus latus
Brevipalpus australis
Panonychus citri


Top